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Cochrane review of COVID-19 vaccines shows they are effective
WEBDec 7, 2022 · Most trials were no longer than two months in length. The review found that the following vaccines reduced or probably reduced the risk of COVID-19 infection compared to placebo: Pfizer/BioNTech, Moderna, CureVac COVID-19, Oxford-AstraZeneca, Janssen, Sputnik V (Gam-COVID-Vac), Sinopharm (WIBP CorV and BBIBP-CorV), Bharat (Covaxin), Novavax and ...
How accurate are rapid antigen tests for diagnosing COVID-19?
WEBAccurate rapid diagnostic tests for SARS-CoV-2 infection would be a useful tool to help manage the COVID-19 pandemic. Testing strategies that use rapid antigen tests to detect current infection have the potential to increase access to testing, speed detection of infection, and inform clinical and public health management decisions …
Oral painkillers available without prescription for acute pain
WEBNon-prescription (over-the-counter, or OTC) analgesics (painkillers) are used frequently. They are available in various brands, package sizes, formulations, and dose. They can be used for a range of different types of pain, but this overview reports on how well they work for acute pain (pain of short duration, usually with rapid onset).
Duloxetine for treating painful neuropathy, chronic pain or
WEBThe usual dose of duloxetine is 60 mg. At this dose, there was moderate quality evidence that duloxetine reduced pain in both painful diabetic peripheral neuropathy and fibromyalgia. In diabetic peripheral neuropathic pain, a 50% or better improvement with duloxetine 60 mg per day was just over one and a half times more likely than with placebo.
What are the benefits and risks of vaccines for preventing COVID …
WEBDec 7, 2022 · Key messages. – Most vaccines reduce, or probably reduce, the number of people who get COVID-19 disease and severe COVID-19 disease. – Many vaccines likely increase number of people experiencing events such as fever or headache compared to placebo (sham vaccine that contains no medicine …
What are the benefits and risks of giving corticosteroids to …
WEBWe used standard Cochrane Pregnancy and Childbirth methods for data collection and analysis. Two review authors independently assessed trials for inclusion, assessed risk of bias, evaluated trustworthiness based on predefined criteria developed by Cochrane Pregnancy and Childbirth, extracted data and checked them for accuracy, and assessed the certainty of the evidence using the GRADE approach.
Bupropion for attention deficit hyperactivity disorder (ADHD
WEBBupropion may be an alternative treatment for adults with ADHD who cannot or will not take stimulant drugs. Quality of the evidence. The quality of the evidence in this review is low, because we found very few studies; five of the six studies were small, and all were poorly conducted. The effect of bupropion on various aspects of daily ...
Which anticholinergic drug for overactive bladder symptoms
WEBThe review found that there are several anticholinergic drugs prescribed for adults with overactive bladder symptoms. The two most studied drugs are oxybutynin and tolterodine. These two drugs have similar effects but, on average, those taking oxybutynin were more likely to withdraw from the studies because of adverse effects, mainly dry mouth.
Donepezil for people with dementia due to Alzheimer's disease
WEBDonepezil is one of these medicines. It is taken as a pill once a day. In Alzheimer's disease, one of the changes in the brain is a reduced number of nerve cells called cholinergic neurones. These are nerve cells that signal to other cells using a chemical called acetylcholine. Acetylcholinesterase inhibitors, such as donepezil, work by ...