A major unresolved challenge to curing HIV-1 is its presence in the nucleus of infected cells. This study reports on new ...
In this issue, Papismadov et al (2024) report that p21 (CDKN1A), known to activate the senescence growth arrest, also ...
The systemic regulation of metabolic dysfunction-associated liver disease remains poorly understood. In this issue, Hsiao et al (2024) identify PCPE-1 as a brown-adipose tissue-derived mediator of ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Aurora-A is an essential cell-cycle kinase ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The precise organization of pre- and ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Evidence suggests mitochondrial homeostasis ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Protein copy numbers constrain systems-level ...
The intracellular bacterial pathogen Coxiella burnetii secretes an effector protein, CbEPF1, which manipulates LD metabolism ...
Reduction of chromosomal instability and inflammation is a common aspect of adaptation to aneuploidy
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Aneuploidy, while detrimental to untransformed ...
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