We applied a computational biophysical model simulating the intracellular ion and IP 3 signaling and diffusion in those 3D cell geometries. The cells were stimulated with three different glutamate ...
Multiple roles of mitochondrial autophagy receptor FUNDC1 in mitochondrial events and kidney disease
The structural characteristics of FUNDC1 enable it to respond to intracellular signal changes and regulate ... participating in mitochondrial fission, maintaining the homeostasis of iron and proteins ...
Furthermore, we show that activated CD4 + T cells deficient in intracellular copper exhibit increased KCa3.1 histidine phosphorylation and channel activity, leading to increased calcium flux and ...
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