The San Francisco 49ers got a taste of what their defense looks like without Nick Bosa in the second half of a loss to ...

The injury-prone San Francisco 49ers are monitoring yet another health issue, this one involving quarterback Brock Purdy's ...

Meanwhile, Harbaugh is in Los Angeles, coaching the Chargers to a 7-3 record, with quarterback Justin Herbert looking like a ...

Enduring unprecedented circumstances, RT Abraham Lucas and C Olu Oluwatimi were positive additions to the Seattle Seahawks' offensive line in Week 11.

The San Francisco 49ers expect tight end George Kittle to practice Wednesday and cornerback Charvarius Ward has returned to ...

Brock Purdy is dealing with soreness in his right (throwing) shoulder, coach Kyle Shanahan said Monday, and is day-to-day.

Quarterback Brock Purdy is day-to-day with a sore right shoulder, and EDGE Nick Bosa will be evaluated throughout the week ...

The oddsmakers are starting to lose confidence in the 49ers. For the first time since last year, the 49ers are underdogs for ...

San Francisco 49ers head coach Kyle Shanahan has offered an update on the injuries to Nick Bosa and Brock Purdy.

Bosa (hip) has about a 50-50 chance to suit up next week against the Packers, Nick Wagoner of ESPN.com reports. The defensive end sustained the hip injury during Sunday's 20-17 loss to the Seahawks ...

The San Francisco 49ers got a taste of what their defense looks like without Nick Bosa in the second half of a loss to ...

The San Francisco 49ers are dealing with a handful of injuries following a disastrous Week 11 loss to the Seattle Seahawks. A ...